CONJUGATES OF STREPTOCOCCUS POLYSACCHARIDE GROUP B AND PROTEIN, METHODS FOR PRODUCING CONJUGATES, IMMUNOGENIC COMPOSITIONS CONTAINING CONJUGATES, AND THEIR USE Russian patent published in 2019 - IPC C07K16/12 A61K39/09 A61K39/39 A61K39/40 A61K47/10 A61K47/26 

FIELD: biotechnology.

SUBSTANCE: described is a group of inventions comprising an immunogenic composition for inducing an immune response against group B streptococcus (versions), a method for inducing an immune response to group B streptococcus, method for preventing or relieving a disease or condition associated with group B streptococcus, a method for producing an antibody, a method of providing passive immunity to a subject, where all said methods involve administering an immunogenic composition. In one embodiment, the immunogenic composition comprises polysaccharide-protein conjugates, wherein the conjugates contain group B streptococcus capsular polysaccharides Ia, Ib, II, III, IV, V, wherein at least one capsular polysaccharide contains sialic acid level higher than 60 %. In another embodiment, the conjugates contain capsular polysaccharides of group B streptococcus serotypes Ia, Ib, II, III, V, VI, VII, VIII, IX.

EFFECT: invention extends the range of agents for inducing an immune response to group B streptococcus.

42 cl, 25 dwg, 36 tbl, 16 ex