FIELD: medicine.
SUBSTANCE: invention relates to medicine, namely to experimental pathophysiology, and concerns simulating of secondary posthypoxic immunodeficiency of disregulatory type with transient failure of CD4-positive lymphocytes. For this purpose, animals are placed for 40–45 minutes in conditions of interval normobaric atmospheric hypoxic hypoxia with hypercapnia until occurence of pre-agonistic state. Specified action is performed for 17 days every 24–48 hours.
EFFECT: method provides significant disturbance between cells of main T-lymphocyte subpopulations with primary failure of CD4-positive cells in peripheral blood, most frequently occurring in structure of secondary immunodeficiency states.
1 cl, 3 tbl, 12 dwg
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