FIELD: biotechnology.
SUBSTANCE: invention relates to biotechnology and immunology. Antibodies are described, which specifically bind to human CD37 and macaque CD37. Immunoconjugate, consisting of antibody and cytotoxic agent, and application of antibody or immunoconjugate for treating oncological disease are also described.
EFFECT: disclosed group of inventions can be used in medicine.
25 cl, 32 dwg, 11 tbl, 17 ex
| Title | Year | Author | Number |
|---|---|---|---|
| CD37-BINDING MOLECULES AND THEIR IMMUNOCONJUGATES | 2011 |
|
RU2742743C2 |
| ANTIBODIES TO FOLIC ACID RECEPTOR 1, THEIR IMMUNOCONJUGATES AND APPLICATION | 2011 |
|
RU2610663C2 |
| ANTIBODIES AGAINST FOLIC ACID RECEPTOR 1, THEIR IMMUNOCONJUGATES AND USE | 2011 |
|
RU2740479C2 |
| CONJUGATION METHODS | 2010 |
|
RU2765240C2 |
| METHODS OF CONJUGATION | 2010 |
|
RU2595424C2 |
| ANTI-CD20 ANTIBODIES AND THEREOF APPLICATION | 2011 |
|
RU2573994C2 |
| ANTI-MESOTHELIN IMMUNOCONJUGATES AND USE THEREOF | 2010 |
|
RU2575612C2 |
| ANTI-CD138 IMMUNOCONJUGATES AND USING THEM | 2008 |
|
RU2547939C2 |
| ANTIBODIES TO FcRH5, THEIR IMMUNOCONJUGATES AND METHODS OF THEIR USE | 2010 |
|
RU2583270C2 |
| CD138-TARGETED CELL AGENTS AND USING THEM | 2008 |
|
RU2537265C2 |
