PROCESS FOR PRODUCTION OF REDUCED FORM OF COENZYME Q Russian patent published in 2017 - IPC A61K8/35 A61K9/14 A61K31/122 C07C41/26 

FIELD: pharmacy.

SUBSTANCE: invention relates to a method for producing reduced form of coenzyme Q₁₀, including (i) reduction of the oxidized form of coenzyme Q₁₀ by preparing a coenzyme Q₁₀ saturated ethanolic solution with dissolved coenzyme Q₁₀ and ascorbic acid at their weight ratio of 1:0.5-2 in the presence of undissolved molten coenzyme Q₁₀ at the temperature of 50-70°C with the addition of the catalyst - ions Cu²⁺ ; (ii) inhibiting the reaction by the addition of complexing compound with Cu²⁺ ; (iii) cooling the mixture, the precipitation and crystallization of the reduced form of coenzyme Q₁₀ as a white sediment; (iv) repeated flushing of the obtained sediment with water; (v) filtration under nitrogen flow; (vi) drying.

EFFECT: obtaining the reduced coenzyme Q₁₀ in the form of the storage stable chemically pure substance, suitable for medical and other applications.

6 cl, 6 ex