FIELD: pharmacology.
SUBSTANCE: group of inventions refers to application of low molecular peptide mimetics of the nerve growth factor: hexamethylenediamide bis-(N-monosuccinyl-glutamyl-lysine) - GC-2 compound; hexamethylenediamide bis-(N-acetyl-lysyl-glutamic acid) - GC-4 compound; amide N-aminocaproyl-glycyl-lysine - GC-5 compound; hexamethylenediamide bis-(N-aminocaproyl-glycyl-lysine) - GC-6 compound as compounds with angiogenic activity.
EFFECT: creation of new highly effective means to stimulate neoangiogenesis at different ischemic processes.
4 cl, 3 dwg, 2 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SUBSTANCE WITH ANTI-ANGIOGENIC ACTIVITY | 2013 |
|
RU2625752C2 |
| SMALL MOLECULES WITH NGF-LIKE ACTIVITY AND ANTIDIABETIC PROPERTIES | 2013 |
|
RU2613314C2 |
| HEPATOPROTECTIVE EFFECT OF LOW MOLECULAR WEIGHT MIMETICS NGF | 2022 |
|
RU2790828C1 |
| PHARMACEUTICAL COMPOSITION OF NEUROPROTECTIVE ACTION FOR PARENTERAL APPLICATION ON BASIS OF HEXAMETHYLENEDIAMINE BIS-(N-MONOSUCCINYL-L-GLUTAMIL-L-LYSINE) IN LYOPHILIZED DOSAGE FORM | 2017 |
|
RU2678203C2 |
| PHARMACEUTICAL COMPOSITION OF NEUROPROTECTIVE ACTION FOR ORAL ADMINISTRATION BASED ON HEXAMETHYLENE AMIDE BIS-(N-MONOSUCCINYL-1-GLUTAMYL-L-LYSINE) (VERSIONS), MADE IN FORM OF A TABLET DISPERSIBLE IN THE ORAL CAVITY | 2018 |
|
RU2740754C1 |
| LOW-MOLECULAR MIMETIC BDNF AS AN AGENT FOR TREATING OPIOID DEPENDENCE | 2019 |
|
RU2707301C1 |
| DRUG PREPARATION WITH ANTIARRHYTHMIC AND ANTIFIBRILLATORY ACTION | 2010 |
|
RU2477144C2 |
| PHARMACEUTICAL COMPOSITION BASED ON BIS-(N-MONOSUCCINYL-L-SERYL-L-LYSINE) HEXAMETHYLENEDIAMIDE (GSB-106) | 2018 |
|
RU2697254C1 |
| DIMERIC DIPEPTIDE MIMETICS OF NEUROTROFIN-3 | 2022 |
|
RU2800369C1 |
| DRUG PREPARATION WITH CARDIOPROTECTIVE ACTIVITY | 2010 |
|
RU2476224C2 |
