FIELD: biotechnology.
SUBSTANCE: invention relates to the new biologically active molecules containing dipeptides, and can be used in medicine. The invention discloses the possibility to obtain compounds characterized by the general formula (R-CO-L-AK-X-Asn-NH-)2(CH2)6, where R = HOOC-(CH2)2-, or HOOC-(CH2)3-, or HO-(CH2)3-, AK = Glu or Asn, X = L- or D-configuration of the corresponding amino acid residue. Such compounds are dimeric dipeptide mimetics of the 4th loop of neurotrophin-3 (NT3).
EFFECT: invention can be used in medical practice in the treatment of depression and various neurodegenerative diseases.
7 cl, 13 ex, 14 tbl
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| SUBSTITUTED DIPEPTIDES WITH NEUROPSYCHOTROPIC ACTIVITY | 2014 |
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| DEOXYURIDINE TRIPHOSPHATES MARKED WITH ZWITTERIONIC INDOCYANINE DYES | 2017 |
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| IMPROVED CONJUGATES N4 OF CHELATING AGENTS | 2005 |
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