METHOD FOR ALTERNATIVE TREATMENT OF INSULIN-PRODUCING PANCREAS BENIGN TUMOUR Russian patent published in 2017 - IPC A61B18/14 A61K38/31 A61P35/00 A61B8/08 G01N33/48 

FIELD: medicine.

SUBSTANCE: for an alternative treatment of insulin-producing pancreas benign tumour, a research of immunoreactive insulin and C-peptide level is conducted. If the parameters exceed their reference values, tumour location is identified, and tumour radiofrequency thermoablation is performed with hormonal parameters monitoring. Preliminary medical therapy by 0.1 mg of octreotide injected subcutaneously 1 time per day is performed for 3 days prior to radiofrequency thermoablation. Radiofrequency thermoablation is carried out in two stages. At the first stage, radiofrequency thermoablation of the central part of the localized tumour is performed for 3 minutes at a temperature of 85-100 degrees Celsius and power 70-90 Wt under intraoperative ultrasonography supervision. The exposure is carried out at RF electrode conductors introduced to a depth of 0.4-0.7 cm . At the second stage, repeated RF thermoablation of the entire tumour within the boundaries of its detected contouris is performed with the same modes of time, temperature and power.

EFFECT: persistent therapeutic effect due to minimally invasive organ-saving and almost complete destruction of tumour at low risk of intra- and postoperative complications, normalization of hormonal status.

5 tbl, 5 ex