METHOD FOR TREATMENT OF PRIMARY LOCALIZED MALIGNANT NEUROENDOCRINAL TUMOURS OF PANCREAS HEAD Russian patent published in 2017 - IPC A61B6/03 A61B17/00 A61M5/00 A61K31/704 A61K49/18 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention can find application in treatment of resectable malignant neuroendocrine tumours (NET) of the pancreas head (PH). 5-6 days before radical removal of the tumour, intraarterial oily chemoembolization of the pancreas head vessels is performed using 0.3 mg/kg of doxorubicin in 5-6 ml of lipidol. After surgical removal of the tumour, a dynamic observation of the patient by positron emission tomography (PET) of the whole body with radiopharmaceutical (RP) Ga-68 DOTATATE is performed. When its pathological accumulation in the form of a local recurrent tumour is revealed, it is removed. When NET metastasis is detected, it is either removed or intraarterial oily chemoembolization with doxorubicin in a dose of 0.5-0.7 mg/kg in 5-6 ml of lipidol is carried out, followed by dynamic observation of the patient by means of whole-body PET with Ga-68 DOTATATE. At that, Ga-68 DOTATATE is used at a dose of 1.5 MBq, but not less than 100 MBq per administration.

EFFECT: method provides timely antitumor treatment and reduces the possibility of local recurrence.

2 cl, 2 ex