ASEPTIC ISOLATED UNIT Russian patent published in 2017 - IPC B01L1/04 F24F3/16 F24F7/06 E04B5/48 E04B9/02 

FIELD: medicine.

SUBSTANCE: invention refers to production of vaccines using pathogenic biological agents (PBA) and can be used for design of isolated aseptic processing facilities for medical, pharmaceutical and microbiological industry. The unit comprises enclosing constructions of the existing facilitit, supply and exhaust ventilation system with high efficiency filters, collapsible building envelope, sealed doors, clean area, downcoming channel filter. Operating facilities including isolation ward premises followed by pre-isolation ward premises, barrier zone premise comprising a controlled barrier zone premise, service premise and vestibule are constructed inside the enclosing structures of the existing facility, on its floor, by means of the sealed mobile enclosing structures. The front wall of the isolation ward and side walls of the unit are adjacent to the ceiling of the existing premises. The controlled barrier zone premise is formed by the front wall of the isolation ward, part of the unit side walls and the outer wall of the existing building. A pass box is installed in the peripheral wall of the isolation ward. The pre-isolation ward premise is shorter than the isolation ward, forming together with a part of the isolation ward peripheral wall, a part of the unit lateral wall and the pre-isolation box side wall a passage to the pass box in the peripheral wall of the isolation ward. The shared ceiling of isolation ward and pre-isolation ward premises is made below the ceiling of the existing premises, forming a ceiling cavity above these two premises with an access provided to the ceiling cavity from the service premise. Service premise entrance is equipped with an entrance vestibule with sealed mobile enclosing structures adjacent to the inner wall and ceiling of the existing premises. A downcoming channel, equipped with a high efficiency filter is located at the top of the sealed mobile enclosing structures of the vestibule; the channel connects the vestibule to the service premise. The corner air intake module of the service premise is connected to the air intake duct of the supply ventilation system. The service premise is connected to the controlled barrier zone premise by a downcoming channel equipped with a high efficiency filter and installed in the upper part of the front wall of the isolation ward premise. Air supply ducts of the supply ventilation system in the vestibule, service premise, isolation ward and pre-isolation ward premises are equipped with stand-alone air-distributing modules with high efficiency filters. The sealed door on the peripheral wall of the pre-isolation ward and the sealed door on the peripheral wall of the isolation ward are maximally displaced relatively to each other.

EFFECT: invention provides a possibility to block a possible exit of PBA-contaminated air environment from the isolation ward to the pre-isolation ward and into the surrounding atmosphere, the required class of ambient air cleanliness in the working area of isolation ward and pre-isolation ward at a regulatory regime of air dilution, as well as energy saving in terms of heat (cold) of ambient air in the service premise and vestibule.

5 cl, 5 dwg