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(19)

(11)

2 615 463

(13)

(51)

IPC

C12N15/113(2010-01-01)

A61K31/7105(2006-01-01)

A61P11/06(2006-01-01)

(21) (22)

Application

2016102819, 2016-01-28

(24)

Start date

2016-01-28

(22)

Actual filing date

2016-01-28

(45)

Published

2017-04-04

(72)

Inventor

Andreev Sergej MikhajlovichShilovskij Igor PetrovichSundukova Mariya SergeevnaMaerle Artem VladimirovichSergeev Ilya Viktorovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Uchrezhdenie Nauchnyj Tsentr Immunologii" Federalnogo Mediko-Biologicheskogo Agentstva Rossii

METHOD FOR ALLERGIC BRONCHIAL ASTHMA TREATMENT, BASED ON CYTOKINES IL-4 AND IL-13 GENES EXPRESSION INHIBITION USING SIRNA MOLECULES Russian patent published in 2017 - IPC C12N15/113 A61K31/7105 A61P11/06

Abstract RU 2615463 C1

FIELD: biotechnology.

SUBSTANCE: method comprises intranasal or inhalational administration of an effective amount of agent comprising a mixture of siRNA molecules that suppress gene IL-13 and IL-4 expression.

EFFECT: invention improves the efficiency of allergic asthma treatment.

2 cl, 11 dwg, 2 tbl, 4 ex

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RU 2 615 463 C1

Authors

Andreev Sergej Mikhajlovich

Shilovskij Igor Petrovich

Sundukova Mariya Sergeevna

Maerle Artem Vladimirovich

Sergeev Ilya Viktorovich

Dates

2017-04-04—Published

2016-01-28—Filed