METHOD FOR PREVENTING AND TREATING BRONCHIAL ASTHMA, COMPLICATING RESPIRATORY VIRAL INFECTIONS AND OTHER RESPIRATORY INFLAMMATORY DISEASES Russian patent published in 2014 - IPC A61K38/10 A61P11/06 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to therapy and infectious diseases, and can be used for preventing and treating bronchial asthma, complicating respiratory viral infections and other respiratory inflammatory diseases. That is ensured by a combined inhibition of p-gene of the respiratory syncytial virus (further - RSV) and anti-inflammatory murine il-5 gene; p-gene of the RSV required for the cell replication is inhibited using a created molecule of small interfering RNA (siRNA) - SEQ ID NO 1 (siP1), while anti-inflammatory murine il-5 gene is inhibited using a created molecule of siRNA - SEQ ID NO 15 (siIL4-408). They are used to develop preparations containing therapeutically effective amounts thereof to be used intranasally.

EFFECT: method enables relieving signs of the allergic inflammation and a severity of RSV-infection by inhibiting anti-inflammatory murine il-5 gene and inhibiting the RSV virus replication.

2 cl, 17 dwg, 2 tbl