MEASURING AND MONITORING ELECTRODES WITH APTAMER COATING AND METHODS OF THEIR APPLICATION FOR BIOMARKERS RECOGNITION Russian patent published in 2017 - IPC G01N33/53 

Abstract RU 2617535 C2

FIELD: medicine.

SUBSTANCE: group of inventions relates to the field of molecular diagnostics and can be used to diagnose diseases through molecular biomarkers. The device for specific target molecules or biomarkers detection by detecting of changes in electrical properties includes the following: a measuring sensor with conductive or semi-conductive structure; an electrode system transmitting the signal from the device; and a control sensor with a structure identical to the measuring sensor, but secure, i.e. preventing establishment of communication with the biomarker and acting as a built-in standard. The measuring sensor structure includes aptamer coating and is capable of forming a bond with a biomarker, causing a change in electrical properties. The group of inventions also relates to a method for sample analyzing for the presence of target molecules or biomarkers through the said device.

EFFECT: group of inventions provides increased analyses reliability.

30 cl, 17 dwg, 3 ex

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RU 2 617 535 C2

Authors

Kesh Stefen Li

Robson Kejt

Kinlokh Yan Entoni

Stokli Piter Dzhordzh

Dates

2017-04-25Published

2012-04-02Filed