MODIFIED PEPTIDES AND THEIR APPLICATION FOR TREATMENT OF AUTOIMMUNE DISEASES Russian patent published in 2017 - IPC C07K14/47 A61K38/17 A61P37/06 

Abstract RU 2620070 C2

FIELD: medicine, pharmacy.

SUBSTANCE: this invention relates to the field of biotechnology, particularly to an immunosuppressive agent, and can be used for the treatment of systemic lupus erythematosus (SLE). A peptide is obtained, consisting of the amino acid sequence IHMVYSKRSGKPRGYAFIEY [SEQ ID NO: 2] in which serine in position 9 is phosphorylated and methionine in position 3 is oxidized or of RIHMVYSKRSGKPRGYAFIEY [SEQ ID NO: 1], in which serine in position 10 is phosphorylated and methionine in position 4 is oxidized.

EFFECT: invention provides peptide or salt thereof, effective in systemic lupus erythematosus treatment.

8 cl, 6 dwg, 4 tbl, 4 ex

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RU 2 620 070 C2

Authors

Myuller Silvian

Brian Zhan-Pol

Tsimmer Robert

Dates

2017-05-22Published

2011-12-13Filed