METHOD FOR INTRAOPERATIVE PROPHYLACTIC TREATMENT OF ISCHEMIC DAMAGE TO PANCREAS AND LIVER IN CASE OF COMBINED SHOCK-PRODUCING INJURY Russian patent published in 2017 - IPC A61B17/00 A61K31/515 A61K31/245 A61K31/02 A61K38/57 A61K31/4412 A61M25/00 A61P43/00 

FIELD: medicine.

SUBSTANCE: method of cannulation of the splenic artery and splenic vein is used after the performed splenectomy to perform regional intra-arterial and intravenous perfusion therapy. Solutions are injected at a volumetric rate that allows the fastest possible normalisation of the systemic blood pressure, which should not be less than 70 mm Hg. At that, up to 60% of the infusion volume is injected through the arterial access, and intraarterial infusion includes perfluorane - 400.0 ml, 0.25% novocaine solution 100.0, 0.9% NaCl solution 400.0 and Contrykal 300 thous. units, Ringer's solution 500.0 and mexidol 300 mg, 0.9% NaCl solution 400.0 and 5-fluorouracil 500 mg; perfluorane 400.0 ml, reopolyglucin 400 ml, gelafusin 500 ml are injected simultaneously intravenously. Infusion is performed in a thermostated version at 37ºC at the background of local hypothermia of the pancreatobiliary zone. In a situation requiring application of the technique of stepwise "damage control" interventions, catheters for intra-arterial and intravenous infusion are withdrawn to the anterior abdominal wall, continuing the regional anti-shock therapy as part of the anti-shock therapy complex. A laparostome is applied. On day 2-3, programmed relaparotomy is performed. The final amount of intervention is performed on the abdominal organs, vessels catheterization is eliminated, arterial and venous accesses are ligated.

EFFECT: method allows to reduce the frequency of acute traumatic pancreatitis and acute hepatic insufficiency in case of combined shock-producing injury, to increase the survival rate of patients of young and middle working age with severe shock-associated injuries, to exclude severe stage complications of traumatic disease, to reduce lethality in this category of victims.

2 cl, 2 ex, 3 dwg