METHOD FOR LIPOPROTEINS SYNTHESIS RESEARCH Russian patent published in 2017 - IPC G01N33/49 G01N33/50 

FIELD: medicine.

SUBSTANCE: to study the lipoproteins synthesis in the blood plasma in the evening before bedtime and in the morning on an empty stomach, content of triglycerides, high-density lipoproteins (HDL), low density lipoproteins (LDL) and very low density lipoproteins (VLDL), hematocrit and blood volume are determined, and then the coefficient (K) is calculated, which allows to assess the state of lipoproteins synthesis by the formula:,

where K is the lipoproteins synthesis coefficient, TG_mor is morning triglycerides content in the plasma, TG_eve is evening triglycerides content in the plasma, HDL_mor is morning high density lipoproteins content of in the blood plasma, LDL_mor is morning low density lipoproteins content in the blood plasma, VLDL_mor is morning very low density lipoproteins content in the blood plasma, HDL_eve is evening high density lipoproteins content in the blood plasma LDL_eve is evening low-density lipoproteins content in the blood plasma, VLDL_eve is evening very low density lipoproteins content in the blood plasma, BCV_mor is circulating blood volume in the morning, Ht_mor is Hematocrit, reflecting formed elements proportion in blood in the morning, BCV_eve is circulating blood volume in the evening, Ht_eve is Hematocrit, reflecting formed elements proportion in blood in the evening. If K is below normal values of 0.93-1.07 for men and 0.87-1.02 for women, the condition is evaluated as reduction of high and very high-density lipoproteins synthesis.

EFFECT: use of the method allows accurate assessment of lipoproteins synthesis.

1 ex