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2 621 866

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IPC

C12P1/06(2006-01-01)

C12N1/20(2006-01-01)

A61K35/66(2015-01-01)

C12R1/01(2006-01-01)

(21) (22)

Application

2016113795, 2016-04-12

(24)

Start date

2016-04-12

(22)

Actual filing date

2016-04-12

(45)

Published

2017-06-07

(72)

Inventor

Dzhavakhiya Vakhtang VitalevichGlagoleva Elena ViktorovnaVoinova Tatyana MikhajlovnaPopova Evgeniya DmitrievnaOvchinnikov Aleksandr IgorevichShobolov Dmitrij LvovichBalabanyan Vadim YurevichChernobrovkin Mikhail Gennadevich

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennostyu Lekarstv"

AMYCOLATOPSIS ORIENTALIS STRAIN - PRODUCERS OF EHREMOMITCIN ANTIBIOTIC AND METHOD FOR EHREMOMITCIN PRODUCTION Russian patent published in 2017 - IPC C12P1/06 C12N1/20 A61K35/66 C12R1/01

Abstract RU 2621866 C1

FIELD: biotechnology.

SUBSTANCE: Amycolatopsis orientalis strain, and a method for ehremomitcin antibiotic production are proposed. Amycolatopsis orientalis strain with high activity of ehremomitcin antibiotic production is deposited in the Russian National Collection of Microorganisms of the Institute of Biochemistry and Physiology of Microorganisms named after G.K. Skryabin, RAS under accession number VKMAc-2717D. Method for ehremomitcin antibiotic preparation includes antibiotic sorption from the culture fluid to the carboxyl cation exchanger Purolite C104 or C106 in H⁺-form, antibiotic elution by ammonia solution, eluate concentration, followed by neutralisation and crystallization as by precipitation by means of isopropanol.

EFFECT: high product yield.

2 cl, 2 tbl, 4 ex

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RU 2 621 866 C1

Authors

Dzhavakhiya Vakhtang Vitalevich

Glagoleva Elena Viktorovna

Voinova Tatyana Mikhajlovna

Popova Evgeniya Dmitrievna

Ovchinnikov Aleksandr Igorevich

Shobolov Dmitrij Lvovich

Balabanyan Vadim Yurevich

Chernobrovkin Mikhail Gennadevich

Dates

2017-06-07—Published

2016-04-12—Filed