FIELD: biotechnology, antibiotics. SUBSTANCE: after termination of biosynthesis antibiotic is sorbed on carboxyl cation-exchange resin KB-2 in salt form and eluted with ammonia solution. Then eluate is neutralized, desalted and passed through sorbent ПТФЭ.. Eremomycin is eluted from sorbent with water, concentrated under vacuum up to content 120-140 mg/ml and crystallized as sulfate. EFFECT: strain indicated above, improved method of production. 2 cl, 2 tbl
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Authors
Dates
1998-05-10—Published
1997-06-18—Filed