DERMAL FILLERS COMPOSITIONS, INCLUDING ANTIOXIDANTS Russian patent published in 2017 - IPC A61K8/67 A61Q19/08 

FIELD: cosmetology.

SUBSTANCE: invention relates to the injected dermal filler, consisting of hyaluronic acid, covalently conjugated with a derivative of vitamin C, selected from ascorbyl 3-aminopropyl phosphate (vitagena), 2-glucoside, L-ascorbic acid (AA2G) or ascorbyl sodium phosphate (AA2R), at that the degree of conjugation is about 3-40 of mole percents. In the particular case the hyaluronic acid may be additionally cross-linked by glycidyl ether of pentaerythritol (Star-PEG epoxide), 3-aminopropyl ether of pentaerythritol (Star-PEG amine) or 1.4-butanediol diglycidyl ether (BDDE). The invention also relates to the dermal filler manufacturing method and to the skin conditions treating, selected from the skin dehydration, lack of skin elasticity and tautness, skin roughness, skin pallor, lines or skin stretching marks and skin wrinkles, by intaking such dermal filler.

EFFECT: creation of improved dermal filler compositions with vitamin C steady release rate.

9 cl, 11 dwg, 2 tbl, 17 ex