FIELD: cosmetology.
SUBSTANCE: group of inventions relates to cosmetology. Proposed is an injectable hydrogel composition for treating skin wrinkles, including hyaluronic acid cross-linked with lysine in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) as a binding agent and N-hydroxysuccinimide (NHS) as an activating agent, wherein the concentration of hyaluronic acid cross-linked with lysine is from 10 mg/ml to 40 mg/ml. Method for treating wrinkles on a patient's skin by administering said injectable hydrogel composition to the dermal area of the patient is also proposed.
EFFECT: group of inventions provides a composition that does not lead to blue when administrated into a dermal area of the patient (Tyndall effect) and has good rheological properties and is biocompatible.
13 cl, 2 dwg, 6 tbl, 18 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SKIN FILLERS COMPOSITIONS | 2012 |
|
RU2638713C2 |
| DERMAL FILLER COMPOSITION FOR SMALL WRINKLES TREATING | 2012 |
|
RU2626513C2 |
| HYALURONIC ACID-BASED COACERVATE HYDROGELS FOR USE IN DERMAL FILLERS | 2016 |
|
RU2750684C2 |
| MODIFIED HYALURONIC ACID, METHOD FOR PRODUCTION THEREOF AND USE THEREOF | 2017 |
|
RU2733444C2 |
| CROSS-LINKED POLYSACCHARIDE COMPOSITIONS IN SITU AND VERSIONS OF THEIR USE | 2016 |
|
RU2734419C2 |
| HYDROGEL CONTAINING HYALURONIC ACID DERIVATIVE MODIFIED WITH GALLOL GROUP AS SUBSTRATE, AND ITS USE | 2018 |
|
RU2778054C2 |
| GEL OF HYALURONIC ACID FOR INTRACUTANEOUS INJECTION | 2007 |
|
RU2448740C2 |
| DERMAL FILLER COMPOSITIONS, INCLUDING ANTIOXIDANTS | 2012 |
|
RU2740454C2 |
| COMPOSITIONS AND METHODS FOR IMPROVING THE APPEARANCE OF SKIN | 2016 |
|
RU2718873C2 |
| HYALURONIC ACID GELS CONTAINING ANALGESIC AGENTS | 2009 |
|
RU2496474C2 |
