METHOD OF TREATING INOPERABLE PANCREATIC ADENOCARCINOMA WITH LIVER METASTASES Russian patent published in 2019 - IPC A61K31/337 A61K31/7068 A61K31/282 A61K31/505 A61P35/00 

FIELD: medicine.

SUBSTANCE: invention refers to medicine and oncology, particularly to a method of treating inoperable pancreatic adenocarcinoma with liver metastases. Method involves intra-arterial infusion introduction of 50 mg/m² oxaliplatin through a catheter into a common hepatic artery for 20 minutes, then bolus suspension 50 mg/m² abraxane in at least 5 ml of lipidol, after which the catheter is reinserted into the celiac and intra-arterially infusion 1,000 mg/m² gemcitabine for one hour with subsequent systemic chemotherapy by oral administration of capecitabine daily at 2,500 mg/m² per day in 2 divided doses in the morning and in the evening for no more than 14 days, and such treatment is carried out not more often than 1 time a month before occurrence of undesirable phenomena of II-III degree or progression of tumor process by criteria RECIST.

EFFECT: invention provides a positive therapeutic effect with a satisfactory state of patients, allowing to continue such treatment more than once.

1 cl, 1 ex