DETERMINATION OF THE CONTENT OF GC-RICH SEQUENCE OF THE GENOM (GC-DNA) IN THE COMPOSITION OF CIRCULATING EXTRACELLULAR DNA OF PERIPHERAL BLOOD PLASMA AS A METHOD OF DETERMINATION OF THE LEVEL OF CELL DEATH IN PREGNANCY Russian patent published in 2017 - IPC G01N33/49 G01N33/50 

FIELD: medicine.

SUBSTANCE: in the circulating extracellular DNA of peripheral blood plasma, the content of the GC-rich genome sequence (GC-DNA), a fragment of the transcribed ribosomal repeat region of a human, is determined by non-radioactive quantitative hybridization. If the content of the repeat is more than 2 times higher than its content in genomic DNA, it is concluded that there is a chronic process in the body, which is accompanied by increased cell death.

EFFECT: invention makes it possible to assess the presence of a latent chronic pathology, which can be caused by external influences.

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