FIELD: biotechnology.
SUBSTANCE: an antibody and fusion protein for use in therapeutic treatment of dogs are presented with specific heavy chain isotypes. The amino acid sequence of the heavy chain mediates the activation of effector functions of the immune system at binding antibodies or fusion protein to the target antigen.
EFFECT: invention can be used for treatment of pathological conditions such as pain, inflammatory conditions and cancer conditions of dogs.
12 cl, 15 dwg, 8 ex
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Authors
Dates
2017-07-28—Published
2012-05-08—Filed