METHOD OF EARLY AND DIFFERENTIAL ELECTROMYOGRAPHIC DIAGNOSTICS OF THE BASIC SYMPTOMS OF PARKINSON DISEASE Russian patent published in 2017 - IPC A61B5/488 A61B5/11 

FIELD: medicine.

SUBSTANCE: performing simultaneous recording of electrical muscle activity signals (EMG) of the upper and lower extremities while keeping the joint angle posture unchanged. From the EMG spectrum, the frequency range of the signal that creates the motor act is singled out. The power spectrum of the signal is calculated by the Fourier transform, the maximum peak is determined on the spectrum and its frequency is determined (F_P) And power (A²_P), and also the power of the constant component of the spectrum (A²₀). A polygon of the distribution of the parameter F_P and determine on it the mode F_Mod and the fraction of the frequency that dominates the spectrum (F_P) in one of the three frequency bands of the spectrum P1 - 3.8-6.4 Hz, P2 - 6.4-9 Hz, P3 - ≥9 Hz. Based on the values obtained the tremor coefficient (K_m) as the ratio of the power of the frequency of the maximum point of the spectrum to the average power of all components of the spectrum frequencies except for A²_P and A²₀, in μV². For values of F_mod≥3≤6.4; K_m≥8; P1≥0.6 diagnose tremor; at F_mod≥6.4≤12; K_m≥5≤30; P2≥0.6 - rigidity; at F_mod≥9≤20; K_m≤6; P3≥0.64; A²_p≤15 - akinesia, with F_mod≥3≤10; K_m≤8; P1≥0.45; P2≥0.2; A²_p≥15 - mixed symptomatic-tremor-rigid form of BP; F_mod≥3≤10; K_m≥5≤30; P1≥0.2; P2≥0.45 rigid-trembling; at F_mod≥6.4≤12; K_m≥5≤15; P2≥0.45; P3≥0.2 is rigid-akinetic; at F_mod≥6.4≤12; K_m≥3≤10; P2≥0.2; P3≥0,45 is akinetic-rigid; at F_mod≤6; K_m≤8; P1≥0,3 - early preclinical tremor; at F_mod≥6; K_m≤5; P2≥0,3; A²_p≥7 - early preclinical rigidity.

EFFECT: method makes it possible to increase the reliability of diagnosis and to determine the specific forms of Parkinson's disease, which is achieved by isolating the informative parameters of the electrical activity spectrum of the muscles creating the motor act and calculating the tremor coefficient.

4 cl, 9 dwg, 2 tbl