FIELD: pharmacology.
SUBSTANCE: invention relates application of 2-morpholino-5-phenyl-6H-1,3,4-thiadiazine composition with ascorbic acid for correction of experimental alloxan diabetes. To do this, 2-morpholino-5-phenyl-6H-1,3,4-thiadiazine is administered to experimental animals (rats) at a dose of 40 mg/kg intramuscularly simultaneously with ascorbic acid at a dose of 20 mg/kg.
EFFECT: effective treatment of diabetes under specific experimental conditions due to the synergistic action of the composition components.
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| Title | Year | Author | Number |
|---|---|---|---|
| USE OF COMPOUNDS OF 1,3,4-THIADIAZINE CLASS AS AGENT FOR CORRECTION OF EXPERIMENTAL ALLOXAN DIABETES | 2014 |
|
RU2597764C2 |
| METHOD FOR ASSESSING LONG-TERM HYPERGLYCEMIA | 2013 |
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| HERBAL MEDICINAL PRODUCT HAVING ENDOTHELIOPROTECTIVE ACTIVITY | 2014 |
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| CORRECTIVE COMPOSITION FOR PATHOLOGIC CARBOHYDRATE, LIPID DISBOLISM AND ANTIOXIDANT ORGANISM STATE INVOLVEMENT | 2008 |
|
RU2360683C1 |
| 2-AMINOPROPYLMORPHOLINO-5-ARYL-6H-1,3,4-THIADIAZINES, DIHYDROBROMIDES AND 2-AMINOPROPYLMORPHOLINO-4-ARYLTHIAZOLES, HYDROBROMIDES SHOWING ANTIAGGREGANT ACTION | 2011 |
|
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| 2-CYCLOALKYLIMINO-5-(4-NITROPHENYL)-1,3,4-THIADIAZINES POSSESSING BIOLOGICAL ACTIVITY AGAINST SMALLPOX VIRUS | 2005 |
|
RU2281946C1 |
| 2-PIPERIDINO-5-(THIENYL-2)- AND 2-PIPERIDINO-5-(THIENYL-3)- 6H-1,3,4-THIADIAZINES HYDROBROMIDES POSSESSING ANTIAGGREGANT ACTION | 2010 |
|
RU2445310C2 |
| 2-CYCLOALKYLAMINO-5-THIENYL-1,3,4-THIADIAZINES, HYDROBROMIDES, WITH ANTIAGGREGANT ACTIVITY | 2008 |
|
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| ANTIDIABETIC AGENT WITH HYPOLIPIDEMIC ACTIVITY FOR TREATMENT AND PREVENTION OF INSULAR DIABETES II TYPE | 2007 |
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