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IPC

C07D417/12(2006-01-01)

A61K31/549(2006-01-01)

A61K31/5377(2006-01-01)

A61K31/427(2006-01-01)

A61P7/02(2006-01-01)

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Application

2011114252/04, 2011-04-12

(24)

Start date

2011-04-12

(22)

Actual filing date

2011-04-12

(45)

Published

2012-07-20

(72)

Inventor

Chupakhin Oleg NikolaevichSidorova Larisa PetrovnaPerova Natal'Ja MikhajlovnaRusinov Vladimir LeonidovichMakarov Vladimir AleksandrovichLogvinova Julija SergeevnaVasil'Eva Tat'Jana Mikhajlovna

(73)

Holder

Federal'Noe Gosudarstvennoe Avtonomnoe Obrazovatel'Noe Uchrezhdenie Vysshego Professional'Nogo Obrazovanija Federal'Nyj Universitet Imeni Pervogo Prezidenta Rossii B.N. El'Tsina"

2-AMINOPROPYLMORPHOLINO-5-ARYL-6H-1,3,4-THIADIAZINES, DIHYDROBROMIDES AND 2-AMINOPROPYLMORPHOLINO-4-ARYLTHIAZOLES, HYDROBROMIDES SHOWING ANTIAGGREGANT ACTION Russian patent published in 2012 - IPC C07D417/12 A61K31/549 A61K31/5377 A61K31/427 A61P7/02

Abstract RU 2456284 C1

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to 2-aminopropylmorpholino-5-aryl-6H-1,3,4-thiadiazines, dihydrobromides (of general formula I) and 2-aminopropylmorpholino-4-arylthiazoles, hydrobromides, (of general formula II) which show antiaggregant activity. wherein R = H; F; CI; Br; OH.

EFFECT: given compounds may be used for preparing cardiologic drugs and enable better treatment of various cardiovascular diseases, including myocardial infarction and thrombotic apoplexy.

1 cl, 2 tbl

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RU 2 456 284 C1

Authors

Chupakhin Oleg Nikolaevich

Sidorova Larisa Petrovna

Perova Natal'Ja Mikhajlovna

Rusinov Vladimir Leonidovich

Makarov Vladimir Aleksandrovich

Logvinova Julija Sergeevna

Vasil'Eva Tat'Jana Mikhajlovna

Dates

2012-07-20—Published

2011-04-12—Filed