FIELD: chemistry.
SUBSTANCE: method comprises adding carbon dioxide gas or solid carbon dioxide (dry ice) gas to a solution containing 4-chloro-2-fluoro-3-methoxyphenyl boronate, an inert organic solvent and at least one lithium salt such that at least one salt Lithium reacted with gaseous carbon dioxide and a mixture containing 4-chloro-2-fluoro-3-methoxyphenyl boronate, an inert organic solvent and a precipitated solid was formed; and removing the precipitated solid from the mixture. A process for the preparation and isolation of dimethyl 4-chloro-2-fluoro-3-methoxyphenyl boronate and a process for using 4-chloro-2-fluoro-3-methoxyphenyl boronate for obtaining 4-acetylamino-3-chloro-6-(4-chloro-4-chloro-2-fluoro-3-methoxyphenyl) pyridine-2-carboxylate.
EFFECT: improving the synthesis efficiency.
14 cl, 2 ex
