FIELD: pharmacology.
SUBSTANCE: invention relates to compositions with a high degree of penetration or prodrugs with a high degree of penetration based on a peptide or a peptide-related compound that contain a functional unit, a linker and a transport unit. The functional unit is covalently bound to the transport unit via the linker and comprises a peptide or peptide-related compound fragment. The transport unit comprises an amino group capable of being protonated. The linker comprises a bond capable of cleavage after composition penetration through a biological barrier.
EFFECT: increased penetration.
27 cl, 2 dwg, 16 tbl, 6 ex
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