FIELD: medicine.
SUBSTANCE: granulocyte-macrophage colony-stimulating factor (GM-CSF) antagonist is used as an analgesic agent to treat pain. At that, the agent is used to treat pain selected from pain due to bone cancer, pain caused by osteoarthritis, and post-operative pain. The antagonist is a GM-CSF specific antibody comprising the amino acid sequence of the heavy chain variable region of SEQ ID NO: 3 and the amino acid sequence of the light chain variable region of SEQ ID NO: 4.
EFFECT: use of the granulocyte-macrophage colony-stimulating factor antagonist is effective for treatment of pain of various genesis.
12 ex, 6 dwg
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|---|---|---|---|
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|
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