FIELD: medicine.
SUBSTANCE: group of inventions relates to medicine, specifically to a method of treating osteoarthritis (OA). That is ensured by using a granulocyte-macrophage colony-stimulating factor (GM-CSF) antagonist to reduce or prevent pathological osteoarthritis symptoms involving cartilage damage, osteophyte formation and joint deformation, where the antagonist is GM-CSF specific antibody.
EFFECT: use of the given group of inventions enables using an antagonist of the granulocyte-macrophage colony-stimulating factor of treating osteoarthritis, particularly manifested osteoarthritis, caused by degenerative processes in the joint and not directly related to the inflammatory component.
7 cl, 6 dwg, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| PAIN TREATMENT | 2009 |
|
RU2712166C2 |
| PAIN TREATMENT | 2009 |
|
RU2630969C2 |
| METHOD OF TREATING MULTIPLE SCLEROSIS | 2010 |
|
RU2539034C2 |
| GM-CSF-NEUTRALIZING ANTIBODIES FOR USE IN TREATING RHEUMATOID ARTHRITIS OR AS ANALGESICS | 2014 |
|
RU2714919C2 |
| TREATING OSTEOARTHRITIS AND PAIN | 2012 |
|
RU2563830C2 |
| ANTI-GM-CSF ANTIBODIES AND USING THEM | 2006 |
|
RU2447085C2 |
| METHODS OF TREATING CONDITIONS WITH ANTIBODIES THAT BIND COLONY STIMULATING FACTOR 1 RECEPTOR (CSF1R) | 2012 |
|
RU2670743C9 |
| METHOD FOR GM-CSFRα INHIBITION IN PATIENT | 2012 |
|
RU2639546C2 |
| ANTIBODIES AGAINST HUMAN CSF-1R AND USES THEREOF | 2012 |
|
RU2658603C2 |
| ANTI-IL-17F ANTIBODIES AND METHODS FOR USE THEREOF | 2010 |
|
RU2605318C2 |
