FIELD: pharmacology.
SUBSTANCE: invention relates to a biodegradable sustained-release lipid concentrate that contains sorbitan unsaturated fatty acid ester having two or more -OH (hydroxyl) groups on the polar head, a phospholipid and a liquid crystal hardener selected from the group consisting of triglyceride, retinyl palmitate, tocopheryl acetate, cholesterol, benzyl benzoate and mixtures thereof. The invention also relates to a pharmaceutical composition for sustained release of active ingredient comprising a pharmacologically active ingredient and a lipid preconcentrate.
EFFECT: lipid preconcentrate is characterized by high safety and biodegradability, sustained release of the active substance.
12 cl, 33 ex, 5 tbl, 5 dwg
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