PHENYLCARBAMATE COMPOUNDS FOR APPLICATION IN EPILEPSY PREVENTION OR TREATMENT Russian patent published in 2017 - IPC C07C271/10 C07C271/12 C07C271/24 A61K31/16 A61P25/08 

FIELD: pharmacology.

SUBSTANCE: pharmaceutical composition for epilepsy prevention or treatment contains an active ingredient represented by a pharmaceutically effective amount of a phenyl carbamate compound represented by chemical formula 1

,

a pharmaceutically acceptable salt, racemate or enantiomer thereof, wherein X is halogen; N is an integer from 1 to 5; R₁ is a linear or branched alkyl group C₁-C₄; A is a carbamoyl derivative represented by the formula -C(O)NHR₂, and B is H; or A is H and B is a carbamoyl derivative represented by the formula -C(O)NHR₃; and R₂ and R₃ may be the same or different and are independently selected from the group consisting of hydrogen, a linear or branched alkyl group C₁-C₄, a cycloalkyl group C₃-C₈ and a benzyl group. The invention also relates to application of a phenyl carbamate compound represented by chemical formula 1, a pharmaceutically acceptable salt, racemate or enantiomer thereof in the manufacture of a medicament for epilepsy treatment.

EFFECT: phenylcarbamate compound application for epilepsy treatment.

4 cl, 5 tbl, 2 dwg, 234 ex