FIELD: chemistry.
SUBSTANCE: proposed invention relates to a method for preparation of 3-(o,m,p-fluorophenyl)-7-methyl-3,4-dihydro-2H-benzo[f][1,5,3]dithiazepines, which can be used as selective ligands, for extraction and separation of metal cations, interphase catalysts modeling enzymatic activity. The essence of the method consists in the interaction of N,N-bis(methoxymethyl)-N-(o,m,p-fluorophenyl)amines with 3,4-dimercaptotoluidine in the presence of the samaric nitrate crystallohydrate catalyst Sm(NO3)3*6H2O, taken in the molar ratio of N,N-bis(methoxymethyl)-N-(o,m,p-halophenyl)amine:3,4-dimercaptotoluidine:Sm(NO3)3*6H2O = 1:1:0.05, at a room temperature (~ 20°C) and atmospheric pressure in ethyl acetate as solvent for 6-8 hours. The yield of the corresponding 3-(o,m,p-fluorophenyl)-7-methyl-3,4-dihydro-2H-benzo[f ][1,5,3]dithiazepines of the general formula 
is 80-94%.
EFFECT: new compounds of general formula 1 are obtained.
1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PRODUCING 3-(O,M,N-HALOGENPHENYL)-3,4-DIHYDRO-2H-BENZO[F][1,5,3]DITHIAZEPINES | 2016 |
|
RU2632661C2 |
| METHOD OF PRODUCING 6-HALOGENPHENYL-2,4,8-TRITHIA-6-AZA-1,3(1,4)-DIBENZOCYCLOOCTAPHANS | 2015 |
|
RU2605430C1 |
| METHOD OF PRODUCING 4-(O,M,P-HALOGENPHENYL)-2,6-DITHIA-4-AZABICYCLO [5,3,1]UNDECA-1(11),7,9-TRIENES | 2016 |
|
RU2626006C1 |
| METHOD OF PRODUCING N-ARYL-1,5,3-DITHIAZACYCLOUNDECANES | 2014 |
|
RU2570207C2 |
| METHOD OF PRODUCING N-ARYL-1,5,3-DITHIAZECANES | 2014 |
|
RU2570206C2 |
| METHOD FOR 7,16,25-TRIARYL-7,8,16,17,25,26-HEXAHYDRO-6H,15H,24H-TRIBENZO[F,M,T][1,5,8,12,15,19]HEXAOXA[3,10,17]TRIAZACYCLOHEXENICOSINES PREPARATION | 2016 |
|
RU2632666C1 |
| METHOD OF PRODUCING 4,18,32-TRIS(o,m,p-HALOPHENYL)-11,25,39-TRIOXA-2,6,16,20,30,34-HEXATHIA-4,18,32-TRIAZAHEPTACYCLO[38.2.2.2.2.2.2.2]TETRAPENTACONTA-1(43),7(54),8,10(53),12(52),13,15(51),21(50),22,24(49),26(48),27,29(47),35(46),36,38(45),40,41-OCTADECAENES | 2014 |
|
RU2561498C1 |
| METHOD OF OBTAINING 3-PYRIDINYL-1,5,3-DITHIAZEPINANES | 2012 |
|
RU2532923C2 |
| METHOD OF PRODUCING N-ARYL-1,5,3-DITHIAZONANES | 2014 |
|
RU2559361C1 |
| METHOD OF PRODUCING 6-ARYL-2,4,8-TRITHIA-6-AZA-1,3(1,4)-DIBENZOCYCLOOCTAPHANES | 2015 |
|
RU2605429C1 |
