DRUG BASED ON 5-AMINO-2,3-DIHYDROPHTHALAZINE-1,4-DIONE AS QUICK-SOLUBLE FILM FOR TRANSBUCCAL INTRODUCTION Russian patent published in 2017 - IPC A61K31/502 A61P17/18 A61P29/00 A61P35/00 A61P37/02 

FIELD: pharmacology.

SUBSTANCE: drug in the form of easily soluble biocompatible film for transbuccal application includes a therapeutically effective amount of pharmacologically active agent, such as a salt of alkaline or alkaline-earth metal 5-amino-2.3-dihydrophthalazine-1.4-dione as a waterless salt or its monohydrate or dihydrate, or their mixtures, mucoadhesive film forming polymer plasticiser and taste flavour, represented by a mixture of β-cyclodextrin or modified β-cyclodextrin with sorbitol when their mass ratio of 4:1-1:2, the content of the specified mixture in the film is 15-40 wt % of the weight of the entire film.

EFFECT: increased release speed of the pharmacologically active agent when applying the film, increased transparency, uniformity and stability in storage while retaining elasticity and strength.

16 cl, 5 tbl