NEW PEPTIDE WITH 4 LINKED CTL-EPITHOPES Russian patent published in 2017 - IPC C07K14/82 C07K19/00 C12N5/783 A61K39/00 A61P35/00 

Abstract RU 2636549 C1

FIELD: biotechnology.

SUBSTANCE: invention can be used in medicine to induce anti-tumour immunity against expression of Lck, WHSC2, SART2, SART3, UBE2V, EGFR, PTHrP or MRP3 cancer. A peptide is obtained from 4 CTL epitopes of cancer antigens linked through amino acid linkers. The resulting peptide is used to stimulate peripheral blood lymphocytes to obtain a combination of CTL specific for the cancer antigen.

EFFECT: invention allows to obtain a peptide vaccine for cancer treatment in a wide range of patients without the necessity of HLA-typing and regardless of the HLA types in patients.

11 cl, 17 dwg, 4 tbl, 5 ex

Similar patents RU2636549C1

Title Year Author Number
EMULSIFIER COMPOSITION AND USE THEREOF 2019
  • Doi Yusuke
RU2793862C2
ANTITUMOR AGENT AND A METHOD OF ITS EVALUATION 2019
  • Tanaka Yuki
RU2803148C2
NOVEL PEPTIDE WITH 5 LINKED CTL EPITOPES 2014
  • Fukaya Satosi
  • Osada Tosikhiro
  • Vada Khirosi
  • Utsugi Terukhiro
RU2627175C2
FELAMENTOUS FUNGI CELL WITH PROTEASE DEFICIT AND METHODS OF ITS APPLICATION 2013
  • Landovski Kristofer
  • Khuuskonen Anne
  • Saarinen Yukhani
  • Vesterkholm-Parvinen Ann
  • Kanerva Anne
  • Natunen Yari
  • Khyanninen Anna-Liisa
  • Salovuori Noora
  • Penttilya Merya
  • Salokhejmo Markku
RU2645252C2
METHOD FOR ENZYMATIC REMOVAL OF BIOFILM, COMPOSITION AND SET 2008
  • Barnett Kristofer
  • Kumar Manodzh
  • Uajted Gregori M.
RU2495098C2
Bcl-2 PROTEINS, FRAGMENTS THEREOF, AND APPLICATION THEREOF IN PATIENTS WITH MALIGNANT TUMOUR 2004
  • Straten Ehjvind Per Tor
  • Andersen Mads Khal'D
RU2367468C2
HJURP PEPTIDES AND VACCINES CONTAINING THEM 2011
  • Nakamura Jusuke
  • Tsunoda Takuja
  • Okhsava Rjudzi
  • Josimura Satiko
  • Vatanabe Tomokhisa
RU2570560C2
PEPTIDE CANCER VACCINES EXPRESSING TUMOUR-SPECIFIC ANTIGENS 2008
  • Tsunoda Takuja
  • Okhsava Rjudzi
RU2464275C2
TEM8 PEPTIDES AND VACCINES CONTAINING THEM 2008
  • Tsunoda Takuja
  • Osava Rjudzi
RU2498993C2
TTK PEPTIDES AND VACCINES CONTAINING THEM 2010
  • Nakamura Jusuke
  • Tsunoda Takuja
  • Okhsava Rjudzi
  • Josimura Satiko
  • Vatanabe Tomokhisa
RU2531348C2

RU 2 636 549 C1

Authors

Fukaya Satosi

Osada Tosikhiro

Vada Khirosi

Dates

2017-11-23Published

2014-10-20Filed