STABILIZED PEMETREXEDE COMPOSITION Russian patent published in 2017 - IPC A61K9/08 A61K31/517 A61K31/519 

Abstract RU 2636783 C2

FIELD: pharmacology.

SUBSTANCE: invention refers to cancer pemetrexed compositions in an airtight container that contains pemetrexed or its pharmaceutically acceptable salt, as the active ingredient, as well as N-acetyl-L-cysteine and sodium citrate, where this the composition has gaseous oxygen content of 3% vol./vol. in the container free space or less relative to the total amount of free space.

EFFECT: invention implementation allows to obtain a stable pemetrexed composition.

7 cl, 14 tbl, 39 ex, 1 dwg

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RU 2 636 783 C2

Authors

Shin Myung Jin

Jin Hong Chul

Park Young Joon

Choi Nak Hyun

Choi Ha Yong

Dates

2017-11-28Published

2014-05-08Filed