FIELD: pharmacology.
SUBSTANCE: invention refers to cancer pemetrexed compositions in an airtight container that contains pemetrexed or its pharmaceutically acceptable salt, as the active ingredient, as well as N-acetyl-L-cysteine and sodium citrate, where this the composition has gaseous oxygen content of 3% vol./vol. in the container free space or less relative to the total amount of free space.
EFFECT: invention implementation allows to obtain a stable pemetrexed composition.
7 cl, 14 tbl, 39 ex, 1 dwg
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Authors
Dates
2017-11-28—Published
2014-05-08—Filed