FIELD: pharmacology.
SUBSTANCE: invention relates to a germanium compound of the general formula (I): Ge[P]x[CA]y, where P is a peptide that is Lys-Glu; CA is a hydroxycarboxylic acid selected from malic acid or citric acid; x=1 for y=1, x=2 for y=0. A method for preparation of a formula (I) compound and a pharmaceutical composition having an immunomodulatory activity comprising a formula (I) compound are also provided.
EFFECT: increased activity of the composition.
15 cl, 6 dwg, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF PREPARING PEPTIDES SHOWING TISSUE-SPECIFIC ACTIVITY AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 2000 |
|
RU2161501C1 |
| ANTIMICROBIAL PEPTIDE | 2014 |
|
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| MODIFIED LIPIDATED RELAXIN B-CHAIN PEPTIDES AND THEIR THERAPEUTIC USE | 2019 |
|
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| KLK5-INHIBITING PEPTIDE | 2019 |
|
RU2826422C2 |
| PEPTIDE NORMALIZING METABOLISM IN OSSEOUS AND CARTILAGE TISSUE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS USING | 2006 |
|
RU2299741C1 |
| PHARMACEUTICAL COMPOSITION CONTAINING INSULIN AND GLUCAGON | 2019 |
|
RU2823246C2 |
| PRODRUG COMPOSITIONS WITH HIGH DEGREE OF PENETRATION BASED ON PEPTIDES AND RELATED COMPOUNDS | 2010 |
|
RU2627065C2 |
| PEPTIDE DERIVED FROM FOXM1, AND INCLUDING ITS VACCINE | 2016 |
|
RU2738418C2 |
| HIGH-PENETRATION PRODRUG COMPOSITIONS BASED ON PEPTIDES AND PEPTIDE-RELATED COMPOUNDS | 2010 |
|
RU2767051C2 |
| METHOD OF OBTAINING PEPTIDES | 0 |
|
SU639446A3 |
