COMPLEX COMPOUNDS OF GERMANIUM WITH PEPTIDES AND PEPTIDES AND HYDROXYCARBONIC ACIDS Russian patent published in 2017 - IPC C07K5/06 C07K5/68 C07K5/08 C07K5/10 C07F7/30 A61K38/05 A61K38/06 A61K38/07 A61K31/28 

Abstract RU 2636788 C2

FIELD: pharmacology.

SUBSTANCE: invention relates to a germanium compound of the general formula (I): Ge[P]x[CA]y, where P is a peptide that is Lys-Glu; CA is a hydroxycarboxylic acid selected from malic acid or citric acid; x=1 for y=1, x=2 for y=0. A method for preparation of a formula (I) compound and a pharmaceutical composition having an immunomodulatory activity comprising a formula (I) compound are also provided.

EFFECT: increased activity of the composition.

15 cl, 6 dwg, 5 ex

Similar patents RU2636788C2

Title Year Author Number
METHOD OF PREPARING PEPTIDES SHOWING TISSUE-SPECIFIC ACTIVITY AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 2000
  • Khavinson V.Kh.
RU2161501C1
ANTIMICROBIAL PEPTIDE 2014
  • Nibbering Petrus Khendrikus
  • Khimstra Piter
  • Drejfkhaut Yan Vauter
RU2695455C2
MODIFIED LIPIDATED RELAXIN B-CHAIN PEPTIDES AND THEIR THERAPEUTIC USE 2019
  • Duclos, Olivier
  • Illiano, Stephane
  • Mallart, Sergio
  • Minoletti-Hochepied, Claire
  • Bianchi, Elisabetta
  • Ingenito, Raffaele
  • Magotti, Paola
  • Santoprete, Alessia
RU2804702C2
PEPTIDE NORMALIZING METABOLISM IN OSSEOUS AND CARTILAGE TISSUE, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS USING 2006
  • Khavinson Vladimir Khatskelevich
  • Grigor'Ev Evgenij Iosifovich
  • Malinin Vladimir Viktorovich
  • Ryzhak Galina Anatol'Evna
RU2299741C1
PHARMACEUTICAL COMPOSITION CONTAINING INSULIN AND GLUCAGON 2019
  • Kim Jung Kuk
  • Lee Jong Suk
  • Dong Joo Young
  • Lee A Ram
RU2823246C2
PRODRUG COMPOSITIONS WITH HIGH DEGREE OF PENETRATION BASED ON PEPTIDES AND RELATED COMPOUNDS 2010
  • Yuj Chunsi
  • Syuj Lina
  • Chen Yujkhua
  • Yan Binbin
  • Tu Shitsyan
RU2627065C2
PEPTIDE DERIVED FROM FOXM1, AND INCLUDING ITS VACCINE 2016
  • Yamashita, Sachiko
  • Hikichi, Tetsuro
RU2738418C2
HIGH-PENETRATION PRODRUG COMPOSITIONS BASED ON PEPTIDES AND PEPTIDE-RELATED COMPOUNDS 2010
  • Yuj Chunsi
  • Syuj Lina
  • Chen Yujkhua
  • Yan Binbin
  • Tu Shitsyan
RU2767051C2
METHOD OF OBTAINING PEPTIDES 0
  • Nedamparambil A.Abrakham
  • Gans Veli Immer
  • Verner Robert Nelson
  • Kazimir Sestandzh
SU639446A3
PEPTIDE ENHANCING RESISTANCE OF CAPILLARIES, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR ITS USING 2006
  • Khavinson Vladimir Khatskelevich
  • Grigor'Ev Evgenij Iosifovich
  • Malinin Vladimir Viktorovich
  • Ryzhak Galina Anatol'Evna
RU2295970C1

RU 2 636 788 C2

Authors

Isaev Aleksandr Dmitrievich

Ambrosov Igor Valerevich

Manasherov Tamaz Omarovich

Matelo Svetlana Konstantinovna

Dates

2017-12-01Published

2016-02-29Filed