METHOD OF PRODUCING BETULINOL DISUCCINATE Russian patent published in 2017 - IPC C07J63/00 C07J75/00 

Abstract RU 2638160 C1

FIELD: chemistry.

SUBSTANCE: invention refers to the meth of of producing disuccinate betulinol of the formula: by acylating betulinol, in which as succinic acid is used as an acylating agent. Acylation is carried out by melting betulinol with succinic acid at a temperature of 185-190°C for 20-25 minutes with a molar ratio of betulinol to succinic acid of 1:3, followed by recrystallization of the desired product from ethanol.

EFFECT: new method of producing betulinol disuccinate is developed, which shortens the duration of the production process, eliminates expensive and toxic reagents.

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RU 2 638 160 C1

Authors

Levdanskij Vladimir Aleksandrovich

Levdanskij Aleksandr Vladimirovich

Kuznetsov Boris Nikolaevich

Dates

2017-12-12Published

2017-03-20Filed