TOPICAL APPLICATION COMPOSITIONS CONTAINING DAPSON AND DAPSONE/ADAPALEN, AND METHODS FOR THEIR APPLICATION Russian patent published in 2017 - IPC A61K9/00 A61K31/136 A61K31/145 A61K31/192 A61K47/10 A61K47/14 A61K47/32 A61K47/34 A61P17/00 A61P17/10 

FIELD: pharmacology.

SUBSTANCE: invention is a dermatological composition containing dapsone, the first solubilising agent, which is monoethyl ether diethylene glycol, polymer thickener and water, where dapsone is present in the composition at a concentration of 3 wt % to 10 wt % and the polymer thickener consists of a acrylamide/sodium acryloyldimethyltaurate copolymer.

EFFECT: reduced particle size of dapsone, which leads to minimized feeling of the presence of sand when applied, and decreased dapsone dissolution in the monoethyl ether of diethylene glycol that leads to a more aesthetic appearance of the composition.

19 cl, 3 dwg, 8 tbl, 6 ex