FIELD: biotechnology.
SUBSTANCE: invention relates to a method of determining whether a patient with hepatitis b (HBV) has an increased probability of a positive outcome of hepatitis B treatment compared to the average probability in a population of patients with hepatitis B. The proposed method includes establishing whether the sample with nucleic acid of specified patient with hepatitis B, associated with positive result of G allele of SNP rs 12356193.
EFFECT: invention allows you to determine whether a patient with HBV will respond to HBV therapy prior to therapy, and gives the possibility to avoid unnecessary expenditure and the emergence of side-effects and complications during treatment.
9 cl, 24 dwg, 3 tbl, 4 ex
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