METHOD OF BETULIN NANOCAPSULES PRODUCTION Russian patent published in 2018 - IPC A61K31/47 A61K35/04 A61K36/185 A61K47/36 A61K9/51 A61J3/07 B01J13/02 B82B3/00 

Abstract RU 2640499 C1

FIELD: nanotechnology.

SUBSTANCE: method for producing betulin nanocapsules is characterized in that an apple or citrus pectin is used as the nanocapsule shell, and betulin is used as the nucleus. According to the method betulin powder is added to a suspension of high- or low-etherified pectin in methanol in the presence of 0.01 g of E472c drug as a surfactant at a stirring speed of 1000 rpm, then hexane is poured in. The resulting suspension pf nanocapsules is filtered and dried at room temperature. The core: shell ratio is 1:1 or 1:3.

EFFECT: according to the invention the method provides simplification and acceleration of the nanocapsules production process and increase in the yield by weight.

2 dwg, 6 ex

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RU 2 640 499 C1

Authors

Krolevets Aleksandr Aleksandrovich

Dates

2018-01-09Published

2016-07-26Filed