FIELD: pharmacology.
SUBSTANCE: invention relates to preparation of new 4-amino-3-methoxymethyl-5-phenyl-1H-pyrazole previously not described. 4-amino-3-methylamide-5-phenyl-1H-pyrazole that has the following equation, derived from cycloaromatization of isonitrosodiketone and restoration of a new, not previously described intermediate - 4-nitroso-3-methylamide-5-phenyl-1H-pyrazole. The resulting target compound shows high antibacterial activity against E. coli (Escherichia coli strain ATCC 25822, sensitive to antibiotics) that allows its use in pharmacology to create antibacterial drugs. 
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EFFECT: increased efficiency of compounds application.
2 ex
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| 5(3)-PHENYL-4-PHENYLAZO-3(5)-PYRAZOLE CARBOXYLIC ACID ELICITING ANTIBACTERIAL ACTIVITY | 2000 |
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