FIELD: biotechnology.
SUBSTANCE: application of physiological lipopolysaccharide produced by the strain of the phototrophic bacterium Rhodobacter capsulatus VKM IBPM RAS B-2381D as a non-toxic factor enhancing the differentiating activity of 1α,25-dihydroxyvitamin D3 when monocytic-like cells are differentiated into monocytes, is proposed.
EFFECT: invention can be used to further differentiate promonocytes and monocytes in clinical and experimental medicine and in development of drugs, in particular for oncology.
2 dwg, 1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| AGENT FOR DIFFERENTIATION OF MONOCYTE-LIKE CELLS | 2014 |
|
RU2590696C2 |
| STRAIN OF RHODOBACTER CAPSULATUS PG - PRODUCER OF LIPOPOLYSSACHARIDE, ENDOTOXIN ANTAGONIST | 2008 |
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| METHOD FOR IDENTIFYING FUNCTIONAL M1 AND M2 PHENOTYPE OF HUMAN MACROPHAGES GENERATED IN VITRO FROM BLOOD MONOCYTES | 2019 |
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| METHOD FOR OBTAINING A SUSPENSION OF SINGLE VIABLE CELLS FROM CELLULAR SPHEROIDS | 2021 |
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| METHOD TO PRODUCE RECOMBINANT ANTI-ANGIOGENIC POLYPEPTIDE | 2012 |
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| METHOD OF OBTAINING TISSUE ENGINEERING STRUCTURE | 2016 |
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RU2661738C2 |
