APPLICATION OF PEPTIDE COMPOUND FOR APOPTOSIS INDUCTION IN A TUMOR CELL Russian patent published in 2023 - IPC C07K7/06 C07K7/08 A61K38/08 A61K38/10 A61P35/00 

Abstract RU 2796104 C1

FIELD: pharmaceutical industry.

SUBSTANCE: invention relates to the use of peptide compound containing amino acid sequence FFSFGGAL to suppress activity of cathepsin S, which causes apoptosis induction in a tumor cell. Invention also relates to the use of peptide compound containing amino acid sequence FFSFGGAL for the preparation of a pharmaceutical composition for inhibition of cathepsin S activity, which causes apoptosis induction in a tumor cell.

EFFECT: therapeutic agent for treatment of diseases associated with impaired expression of cathepsin S and/or BCL-2 family proteins.

2 cl, 8 dwg, 7 ex

Similar patents RU2796104C1

Title Year Author Number
PEPTIDE COMPOUNDS FOR INDUCTION OF APOPTOSIS IN TUMOR CELL 2021
  • Zamiatnin Andrei Aleksandrovich
  • Surinder Mokhan Sund
  • Savvateeva Liudmila Vladimirovna
  • Tarasov Vadim Vladimirovich
RU2785794C2
SPECIFIC PEPTIDE INHIBITORS OF CYSTEINE CATHEPSINS 2020
  • Zamiatnin Andrei Aleksandrovich
  • Rudzhinska Magdalena
  • Parodi Alessandro
  • Savvateeva Liudmila Vladimirovna
  • Gorokhovets Neonila Vasilevna
  • Makarov Vladimir Alekseevich
  • Tarasov Vadim Vladimirovich
RU2752531C1
METHOD FOR DETERMINING AMOUNT OF Bel-2 AND Bax PROTEINS IN VASCULAR WALL IN PATIENTS WITH OBLITERATING ATHEROSCLEROSIS OF ARTERIES OF LOWER EXTREMITIES 2020
  • Kalinin Roman Evgenevich
  • Suchkov Igor Aleksandrovich
  • Klimentova Emma Anatolevna
  • Egorov Andrej Aleksandrovich
  • Pshennikov Aleksandr Sergeevich
  • Shchulkin Aleksej Vladimirovich
  • Mylnikov Pavel Yurevich
  • Gerasimov Aleksandr Andreevich
RU2751822C1
PROAPOPTOSIS PROTEINS-CONTAINING THERAPEUTIC AGENTS 2002
  • Rozenbljum Majkl G.
  • Liu Jujing
RU2319709C2
NEW CHEMICAL COMPOUND THAT STIMULATES PRODUCTION OF HUMAN INTERFERON-BETA BY ACTIVATING STING SIGNALING PATHWAY AND METHOD OF ITS PREPARATION 2023
  • Solopova Olga Nikolaevna
  • Gusev Dmitrij Vasilevich
  • Kosorukov Vyacheslav Stanislavovich
  • Sadovskaya Yana Olegovna
  • Mishina Aleksandra Vladimirovna
  • Zajchenko Danila Mikhajlovich
  • Astafeva Yana Romanovna
  • Moskovtsev Aleksej Aleksandrovich
RU2811736C1
METHOD FOR PRODUCING RECOMBINANT FRAGMENT OF HUMAN PLASMINOGEN POSSESSING ANTIANGIOGENIC ACTION 2011
  • Svistunov Andrej Alekseevich
  • Lutsenko Sergej Viktorovich
  • Fel'Dman Natalija Borisovna
  • Solov'Ev Andrej Ivanovich
RU2458987C1
SMALL MOLECULE INHIBITORS OF THE PHOSPHORYLATED BCL-2-ASSOCIATED DEATH PROMOTER (BAD) 2018
  • Lobi, Piter Edvard
  • Pandej, Vidzhej Kumar
  • Kanchugarakoppal Subbegovda, Rangappa
  • Salundi, Bassappa
  • Chakrabkhavi Dkhanandzhaya, Mokhan
  • Rangappa, Shobit
  • Venkatachalaiakh, Shrinivasa
RU2799873C2
METHOD TO PRODUCE RECOMBINANT ANTI-ANGIOGENIC POLYPEPTIDE 2012
  • Glybochko Petr Vital'Evich
  • Svistunov Andrej Alekseevich
  • Nikolenko Vladimir Nikolaevich
  • Lutsenko Sergej Viktorovich
  • Fel'Dman Natalija Borisovna
  • Solov'Ev Andrej Ivanovich
RU2488635C1
MULTI-EPITOPE POLYPEPTIDE FOR IMMUNIZATION AGAINST MYCOBACTERIUM TUBERCULOSIS 2023
  • Ivanov Roman Alekseevich
  • Reshetnikov Vasilij Vladimirovich
  • Muslimov Albert Radikovich
RU2824195C1
METHOD OF ISOLATION OF HIGH-MOLECULAR PROTEIN ACTIVATION COMPLEX OF HUMAN CASPASE-2 2016
  • Kopeina Gelina Sergeevna
  • Zamaraev Aleksej Vladimirovich
  • Lavrik Inna Nikolaevna
  • Zhivotovskij Boris Davidovich
RU2671510C1

RU 2 796 104 C1

Authors

Zamyatnin Andrej Aleksandrovich

Surinder Mokhan Sund

Savvateeva Lyudmila Vladimirovna

Tarasov Vadim Vladimirovich

Dates

2023-05-17Published

2022-09-16Filed