FIELD: pharmacology.
SUBSTANCE: invention relates to a compound of formula
, where R1 and R2 together with the carbon atom to which they are attached form C3-C10-cycloalkyl; R3 is H or C1-C12-alkyl; R4 is H; W is a bond; A is phenyl substituted by R8, R9 and R10; B is phenyl substituted by R11, R12 and R13; R8 R9 R10 are independently selected from H, halogen-C1-C12-alkyl, halogen; R11, R12 and R13 are independently selected from H, halogen; or pharmaceutically acceptable salts thereof. A pharmaceutical composition, application of a compound of formula (I) and a method for treatment and preventingon of type 2 diabetes, atherosclerosis, cancer, chronic renal failure and non-alcoholic steatohepatitis are also provided.
EFFECT: formula compound inhibits the activity of FABP4 and FABP5 proteins and can be used to treat and prevent the aforementioned diseases.
17 cl, 17 ex
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