ORAL CARE COMPOSITION Russian patent published in 2018 - IPC A61K8/21 A61K8/41 A61K8/362 A61Q11/00 

FIELD: pharmacology.

SUBSTANCE: oral care composition comprising an orally acceptable carrier, a fluoride ion representing amine fluoride and a buffer having pK_a less than 7.0. The buffer contains an aqueous solution of an acid and a salt of this acid where the acid is selected from succinic acid, malic acid, and combinations thereof; pH of the composition for oral administration is 4.2-4.8; the composition has an acid number greater than 6; amine fluoride is olaflur (N-octadecyltrimethylenediamine-N,N,N'-tris(2-ethanol)dihydrofluoride). Methods for application of the above composition, namely the method for fluoride ions delivery to the mouth of a mammal, a method for reduction of cavities formation in the teeth of mammals and a method for teeth remineralization in a mammal. Composition contents comprising the buffer can counteract the buffering effect of saliva and maintain the pH of the composition at a slightly acidic level during composition application.

EFFECT: improved absorption of fluoride from the composition in damages caused by caries, and increased remineralization potential compared to toothpastes corresponding to the current state of art in the field.

14 cl, 3 tbl