1,3-BIS(4-METHOXYBENZOYL)PYRIMIDINE-2,4(1H,3H)-DIONE WITH ACTIVITY ASSOCIATED WITH GLYCATED PROTEINS CROSS LINKAGE BREAKING Russian patent published in 2018 - IPC C07D239/54 A61P3/10 A61P25/28 

Abstract RU 2643520 C1

FIELD: pharmacology.

SUBSTANCE: invention relates to a new compound, namely 1,3-bis(4-methoxybenzoyl)pyrimidine-2,4(1H,3H)-dione corresponding to the structural formula (I) below. Structural formula (I)

.

EFFECT: compounds possess glycated proteins cross-linkage breaking activity and can be used in treatment of diabetes and diseases associated with aging and neurodegenerative amyloid disease, such as Alzheimer's disease.

2 dwg, 2 ex

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RU 2 643 520 C1

Authors

Brel Anatolij Kuzmich

Spasov Aleksandr Alekseevich

Lisina Svetlana Viktorovna

Popov Sergej Sergeevich

Rashchenko Andrej Igorevich

Dates

2018-02-02Published

2017-04-11Filed