FIELD: chemistry.
SUBSTANCE: invention relates to the use of heterocyclic hydrazones of the following general formula as agents having antiglycating activity.
.
EFFECT: said hydrazones suppress the protein glycation and can be used in medicine to treat and prevent the development of diabetes mellitus complications.
1 cl, 2 tbl, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| SODIUM SALT OF DIETHYL ETHER OF 4-OXO-1,4-DIHYDROPYRAZOLO[5,1-C]-1,2,4-TRIAZINE-3,8-DICARBOXYLIC ACID MONOHYDRATE | 2015 |
|
RU2612300C1 |
| INHIBITORS OF FORMATION OF GLYCATION END PRODUCTS BASED ON AZO-DERIVATIVE PHENYLSULPHONIC ACIDS | 2016 |
|
RU2634594C1 |
| BIS[1,2,4]TRIAZOLO[4,3-b:3',4'-f][1,2,4,5]TETRAZINES WITH ANTI-GLYCATING, ANTI-GLYCOXIDATION AND ANTIPLATELET ACTIVITY | 2020 |
|
RU2755897C1 |
| APPLICATION OF SULFASALAZINE AS AN INHIBITOR OF THE FORMATION GLYCATION END PRODUCTS | 2017 |
|
RU2680844C1 |
| SODIUM SALT OF 3-NITRO-4-OXO-1,4-DIHYDROPYRAZOLO[5,1-c]-1,2,4-TRIAZINE-8-CARBOXYLIC ACID, DIHYDRATE | 2016 |
|
RU2641107C1 |
| 3-GUANIDINOAZOLO[1,2,4,5]TETRAZINES HAVING ANTIGLYCATING ACTIVITY AND A PROCESS FOR THEIR PREPARATION | 2017 |
|
RU2668971C1 |
| 2-(5-NITRONYLFURAN-2-YL)-5-METHYL-6-NITRO-1,2,4-TRIAZOLO[1,5-A]PYRIMIDIN-7(4N)-ONE AND SALTS THEREOF | 2018 |
|
RU2716715C2 |
| APPLICATION OF NITRO-DERIVATIVE PHENOL-SULPHONIC ACIDS AS INHIBITORS OF FINAL GLYCATION PRODUCTS FORMATION | 2016 |
|
RU2628605C1 |
| HALIDES OF 1-(4-TERT-BUTYLPHENYL)-2-{3-[2-(4-FLUORO-PHENOXY)ETHYL]-2-METHYL-3H-BENZIMIDAZOLE-1-YL}ETHANONE WITH PROPERTY OF RUPTURE CROSS-LINKERS OF GLYCATED PROTEINS | 2016 |
|
RU2635112C1 |
| PHARMACEUTICAL COMPOSITION OF ANTIGLYCATING ACTIVITY IN SOLID DOSAGE FORM IN FORM OF CAPSULES AND METHOD FOR PREPARATION THEREOF | 2019 |
|
RU2738804C1 |
