FIELD: biotechnology.
SUBSTANCE: invention relates to the field of biotechnology, a vaccine is specifically proposed for the prevention or treatment of a colorectal tumour characterized by microsatellite instability (MSI), which can be used in medicine. The vaccine contains a MSI-specific peptide with a shifted reading frame (SRF), which causes a humoral and cell-mediated response against tumour cells.
EFFECT: vaccine, shown in the present invention, allows for effective prevention and treatment of colorectal cancer.
18 cl, 4 dwg, 1 tbl, 3 ex
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| POLYEPITOPE ANTI-TUMOUR VACCINE STRUCTURE CONTAINING EPITOPES OF TUMOR-ASSOCIATED ANTIGENS, PHARMACEUTICAL COMPOSITION AND ITS APPLICATION FOR STIMULATING SPECIFIC ANTI-TUMOR IMMUNE RESPONSE | 2016 |
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| POLYEPITOPE IMMUNOGENIC POLYPEPTIDES AND METHODS OF APPLICATION THEREOF | 2013 |
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