SYSTEM FOR STABLE EXPRESSION OF TUMOR-ASSOCIATED ANTIGENS BASED ON LENTIVIRAL VECTOR Russian patent published in 2020 - IPC C12N15/867 C12N15/11 C12N15/12 C12N15/62 

Abstract RU 2725493 C2

FIELD: immunology.

SUBSTANCE: disclosed is a lentiviral DNA-based system for stable expression of tumor-associated antigens, followed by transfer into the endosome through a system of the MHC II complex.

EFFECT: present invention can find further application in stimulating the immune system to recognize tumor cells.

3 cl, 3 dwg, 1 tbl

Similar patents RU2725493C2

Title Year Author Number
POLYEPITOPE ANTI-TUMOUR VACCINE STRUCTURE CONTAINING EPITOPES OF TUMOR-ASSOCIATED ANTIGENS, PHARMACEUTICAL COMPOSITION AND ITS APPLICATION FOR STIMULATING SPECIFIC ANTI-TUMOR IMMUNE RESPONSE 2016
  • Sennikov Sergej Vitalevich
  • Maksyutov Amir Zakievich
  • Maksyutov Rinat Amirovich
  • Bakulina Anastasiya Yurevna
  • Gavrilova Elena Vasilevna
  • Kurilin Vasilij Vasilevich
  • Lopatnikova Yuliya Anatolevna
  • Shevchenko Yuliya Aleksandrovna
  • Obleukhova Irina Aleksandrovna
  • Kulikova Ekaterina Vladimirovna
  • Sokolov Andrej Viktorovich
  • Khristin Aleksandr Aleksandrovich
  • Sidorov Sergej Vasilevich
  • Kalichkin Andrej Alekseevich
  • Kozlov Vadim Viktorovich
  • Kiryushina Natalya Anatolevna
  • Cherkasov Andrej Pavlovich
RU2684235C2
METHOD FOR PRODUCTION OF IN VITRO POPULATIONS OF ACTIVATED ANTIGENSPECIFIC ANTITUMOR-TUMOR CYTOTOXIC T-LYMPHOCYTES SPECIFIC TO TUMOR-ASSOCIATED ANTIGEN EPITOPES 2016
  • Sennikov Sergej Vitalevich
  • Lopatnikova Yuliya Anatolevna
  • Kuznetsova Mariya Sergeevna
  • Maksyutov Amir Zakievich
  • Khantakova Yuliya Nikolaevna
  • Kulikova Ekaterina Vladimirovna
RU2619186C1
POLYEPITOPE IMMUNOGENIC POLYPEPTIDES AND METHODS OF APPLICATION THEREOF 2013
  • Maksyutov Amir Zakievich
  • Gavrilova Elena Vasilevna
  • Maksyutov Rinat Amirovich
  • Sennikov Sergej Vitalevich
  • Shevchenko Yuliya Aleksandrovna
  • Kurilin Vasilij Vasilevich
  • Lopatnikova Yuliya Anatolevna
RU2598265C2
GENETIC CONSTRUCT FOR INDUCING PROLIFERATION OF PERIPHERAL MONOCYTES IN VITRO 2017
  • Chumakov Stepan Petrovich
  • Kravchenko Yuliya Evgenevna
  • Frolova Elena Ivanovna
RU2697797C2
BIOMEDICAL CELL PRODUCT FOR TREATMENT OF MALIGNANT NEOPLASMS 2023
  • Kiselevskij Mikhail Valentinovich
  • Chikileva Irina Olegovna
  • Zamkova Mariya Anatolevna
  • Kazanskij Dimitrij Borisovich
  • Persiyantseva Nadezhda Aleksandrovna
  • Khromykh Lyudmila Mendelevna
  • Bruter Aleksandra Vladimirovna
  • Shatunova Polina Olegovna
RU2813531C1
IMMUNOPROPHYLACTIC CANCER VACCINE 2004
  • Agadzhanjan, Majkl, G.
  • Gochikjan, Anait
RU2556128C2
ARTIFICIAL GENE MEL-TCI, CODING POLYEPITOPIC PROTEIN-IMMUNOGENE MEL-TCI, RECOMBINANT PLASMID DNA PMEL-TCI PROVIDING EXPRESSION OF ARTIFICIAL GENE MEL-TCI AND ARTIFICIAL PROTEIN-IMMUNOGENE MEL-TCI, CONTAINING CTL- AND Th-DETERMINANTS OF MELANOMA ANTIGENES RESTRUCTURED BY PLURAL ALLELS HLA OF I AND II CLASS 2017
  • Antonets Denis Viktorovich
  • Borobova Elena Aleksandrovna
  • Ilichev Aleksandr Alekseevich
  • Karpenko Larisa Ivanovna
  • Oreshkova Svetlana Fedorovna
  • Smirnova Olga Yurevna
  • Starostina Ekaterina Vladimirovna
  • Bazhan Sergej Ivanovich
RU2650872C1
PREVENTIVE CANCER VACCINE 2004
  • Agadzhanjan Majkl G.
  • Gochikjan Anait
RU2385163C2
PHARMACEUTICAL COMPOSITION POSSESSING ANTITUMOUR EFFECT, AND METHOD FOR REDUCING PD-L1 INHIBITING EFFECT ON HUMAN T-CELLS 2016
  • Wu Zhao
RU2688692C2
CHIMERIC ANTIGEN RECEPTORS WITH MUTATED CD28 COSTIMULATION DOMAINS 2018
  • Davila, Marko L.
RU2800922C2

RU 2 725 493 C2

Authors

Frolova Elena Ivanovna

Chumakov Stepan Petrovich

Kravchenko Yuliya Evgenevna

Dates

2020-07-02Published

2018-12-28Filed