PEPTIDES OBTAINED FROM p16 FOR PREVENTION AND TREATMENT OF HPV-ASSOCIATED TUMOURS AND OTHER TUMOURS EXPRESSING p16 Russian patent published in 2017 - IPC A61K38/00 A61P37/04 

FIELD: biotechnology.

SUBSTANCE: invention is a fragment of a cyclin-dependent p16^INK4a kinase inhibitor, capable of inducing an immune response against p16^INK4a, a nucleic acid molecule, a vector containing a nucleic acid molecule, a viral vector, as well as their use.

EFFECT: invention allows to increase secretion of interferon-gamma T-cells or induce T-cell proliferation, and use these fragments to immunize an individual against HPV-associated or other types of cancer expressing pl6^INK4a, preferably for the advanced types of cancer.

15 cl, 5 dwg, 1 tbl, 5 ex